Life Updates

A new patch just created will one day monitor a person’s health using minuscule sweat samples. The patch is being developed by Biotex, a consortium of European research institutes and companies, including the Swiss Centre for Electronics and Microtechnology (CSEM).

Most clothing designed for health monitoring focuses on physiological measurements, such as body temperature and heart rate. This is one of the first attempts to continuously analyze biochemical signals using clothing. The team employed a novel approach for monitoring: a combination of hydrophilic and hydrophobic yarns woven together to channel the sweat to the sensors. By utilizing natural attraction and repulsion actions to move the sweat, the method also circumvents the need for additional power sources, which would add bulk to such a device and make it less convenient for everyday use.

Once the fabric has directed a few milliliters of sweat into the patch, the sensors determine the amount of potassium, chloride, or sodium present. Measuring these electrolytes can provide insight into a person’s metabolism. By comparing the electrolyte amounts to reference measurements, such a system could indicate if the user is overexerting herself or stressed, says Jean Luprano, project coordinator at the CSEM.

Once the tiny reservoirs are full of sweat, the user throws away the chemical part of the patch, which is about 5 to 10 square inches. The patch-embedded band or shirt can be washed, and the monitoring electronics reused.  This sounds like sci-fi but it reminds me if the new terminator tv show where the robot can diagnose your physical health by tasting your sweat.

Image courtesy of bfeedme.com Macadamia nuts included in a heart healthy diet reduced low-density cholesterol (bad cholesterol) and should be included among nuts with qualified health claims, according to researchers.

"We looked at macadamia nuts because they are not currently included in the health claim for tree nuts, while other tree nuts are currently recommended as part of a heart healthy diet," says Dr. Amy E. Griel, a recent Penn State Ph.D. recipient in nutrition and now senior nutrition scientist at The Hershey Company. "Macadamia nuts have higher levels of monosaturated fats, like those found in olive oil compared with other tree nuts".

Along with Brazil nuts and cashews, macadamia nuts are not included in the U.S. Food and Drug Administration's list of nuts with qualified health claims because the cut-off point is 4 grams of saturated fat per 50 grams of nuts. Macadamia nuts have 6 grams of saturated fat per 50 grams, cashew nuts have 4.6 grams and Brazil nuts have 7.6 grams of saturated fat per 50 grams of nuts.

"Epidemiological studies showed that people who are frequent nut consumers have decreased risk of heart disease," says Penny Kris-Etherton, co-author and distinguished professor of nutritional sciences.

The researchers used a controlled feeding study to compare a heart-healthy diet with 1.5 ounces a small handful of macadamia nuts to a standard American diet. The participants had slightly elevated cholesterol levels, normal blood pressure and were not taking lipid-lowering drugs. Researchers randomly assigned participants to either the macadamia nut diet or the standard American diet and provided all meals for the participants for five weeks. The participants then switched diets and continued eating only food provided by the researchers for another five weeks.

The Healthy Heart diet with macadamia nuts did reduce total cholesterol, low-density lipoprotein cholesterol and triglyceride levels compared with the standard American diet. The researchers reported in the current issue of the Journal of Nutrition, that the macadamia nuts reduced total cholesterol by 9.4 percent and low-density lipoprotein by 8.9 percent.

Individual calorie levels were used for each participant so that they did not gain or lose weight during the study. Both diets were matched for total fat, containing 33 percent calories from total fat. The Heart Healthy diet with macadamia nuts had 7 percent saturated fat, 18 percent monosaturated fat and 5 percent polyunsaturated fat. The standard American diet had 13 percent saturated fat, 11 percent monosaturated fat and 5 percent saturated fat.

"We found that the reduction in LDL or bad cholesterol we observed was greater than would be predicted by just the healthy fats in the nuts alone," says Griel. "This indicates that there is something else in the nuts that helps lower cholesterol".

The macadamia nut diet included macadamia nuts as a snack, mixed into meals, as a salad topping and in cookies and muffins. The total fat was the same in both diets. Macadamia nuts were substituted for other sources of fat and protein in the diet. Switching skim milk for 2 percent milk and adding some macadamia nuts kept fat levels even.

"I think the bottom line is that Macadamia nuts probably should be included in the list of nuts to have a qualified health claim," says Kris-Etherton.


Posted by: Evelyn    Source

Scientists have pinpointed genetic variations that make people more likely to get hooked on cigarettes and more prone to develop lung cancer — a finding that could someday lead to screening tests and customized treatments for smokers trying to kick the habit.

The discovery by three separate teams of scientists makes the strongest case so far for the biological underpinnings of nicotine addiction and sheds more light on how genetics and lifestyle habits join forces to cause cancer. A smoker who inherits these genetic variations from both parents has an 80 percent greater chance of lung cancer than a smoker without the variants, the researchers reported. And that same smoker on average lights up two extra cigarettes a day and has a much harder time quitting than smokers who don’t have these genetic differences.

The researchers disagreed on whether the variants directly increased the risk of lung cancer or did so indirectly, by causing more smoking. The three studies, funded by governments in the U.S. and Europe, are being published Thursday in the journals Nature and Nature Genetics.

The scientists studied the genes of more than 35,000 white people of European descent in Europe, Canada and the United States. Blacks and Asians will be studied soon and may yield different results, scientists said.They aren’t quite sure if what they found is a set of variations in one gene or in three closely connected genes.

The gene variations, which govern nicotine receptors on cells, could eventually help explain some of the mysteries of chain smoking, nicotine addiction and lung cancer. These oddities include why there are 90-year-old smokers who don’t get cancer and people who light up an occasional cigarette and don’t get hooked. The smoking rate among U.S. adults has dropped from 42 percent in 1965 to less than 21 percent now.

The new studies are surprising in that they point to areas of the genetic code that are not associated with pleasure and the rewards of addiction. That may help explain why some people can quit and others fail, said Dr. Nora Volkow, director of the National Institute of Drug Abuse in Bethesda, Md., which funded one of the studies.

One clue is in the location of the just-discovered variants, on the long arm of chromosome 15, Volkow said. It is in an area that, when damaged during tests on animals, makes them depressed and anxious. While some people smoke because it helps them focus or gives them a physiological reward, others do it to stave off depression.

That suggests that adding antidepressants to some smokers’ treatment could help them kick the habit.  Anti-depressants have been used for quite a while now but I guess they did not know exactly why they worked.

Your friend can eat whatever she wants and still fit into her prom dress, but you gain five pounds if you just look at that chocolate cake. Before you sign up for Weight Watchers and that gym membership, though, you may want to look at some recent research from Tel Aviv University and save yourself a few hundred dollars.

A womans waistline may have less to do with rigorous exercise and abstaining from sweets than it does with the genes of her parents, as per a new study by Prof. Gregory Livshits from the Sackler Faculty of Medicine at Tel Aviv University and his colleagues from Kings College in London. Dr. Livshits and colleagues have found a scientific link between the lean body mass of a woman and her genes. Theyve determined that thinness like your smile or the color of your eyes is an inheritable trait.


Bad News First, Then the Good
Prof. Livshits, whose findings were reported in the Journal of Clinical Endocrinology and Metabolism (2007), says, The bad news is that a number of of our physical features, including our weight, are dependent on our genes. The good news is that women still have an opportunity to go against their genetic constitution and do something about it.

Until now, researchers were not sure to what extent environmental influences and genetics played a role in a womans body size. When controlling for the variance of age, the differences in womens body sizes can be predicted in the genes more than 50 percent of the time, the scientists found.

Prof. Livshits conducted his study on more than 3,000 middle-aged women in the United Kingdom who belonged to either an identical or fraternal twin pair. He measured their total lean mass, one of the three major components of body weight, and compared it to markers in their genes.


A Slim Chance?
Additional collaborative research between the two teams, which builds on the past study, is would be reported in the next few months. It may help pave the way for a skinny gene test, which one day may help women trying to lose weight understand what kind of battle they can expect.

Those without the lean genes, however, will always find it harder to stay slim, predicts Prof. Livshits. But before your diet falls by the wayside, consider Prof. Livshits contention that genetics can be overcome.


Curb Your Enthusiasm
Its important to not have high expectations, he warns. Women need to know that what they can do about their body weight particularly when they age is relatively little, and they will do it only with much difficulty.

Very few studies to date have been able to associate a bodys lean mass with genetics. The topic is a specialty at the Tel Aviv University lab, one of the top labs in the world to study the genetics of aging of body composition. This area includes the study of bone, fat and lean mass as it develops in a person over time.

Research on body composition components their growth, degradation and genes is part of Prof. Livshits ongoing work on aging and health. Issues such as weight gain are complex, he says, particularly when age is factored in.

So dont get too jealous of your friends dress size. It may be mostly out of your hands and in your DNA.


Posted by: Evelyn    Source